The Atherosclerosis Risk in Communities Study is a prospective epidemiological study conducted in four U.S. communities. ARIC is designed to investigate the causes of atherosclerosis and its clinical outcomes, and variations in cardiovascular risk factors, medical care, and disease by race, gender, location, and date. ARIC consists of two parts: a Cohort Component and a Community Surveillance Component....

ALLHAT was a large antihypertensive trial and lipid-lowering trial and included large numbers of patients over age 65, women, African-Americans, and patients with diabetes, treated largely in community practice settings. Participants were men and women aged 55 years and over with a history of hypertension. Data collected includes participant physical measures, demographics, health behaviors, medical...

The Sacramento Area Latino Study on Aging (SALSA) project tracked the incidence of physical and cognitive impairment as well as dementia and cardiovascular diseases in elderly Latinos in the Sacramento region. The effects of hypertension, diabetes, and other cardiovascular risk factors, such as nutrition and lifestyle factors, were also examined.

ACCORD was a large clinical trial examining methods of lowering the rate of cardiovascular disease in adults with type two diabetes. The study was composed of three clinical trials: an intensive lowering of blood sugar levels, intensive lowering of blood pressure, and treatment of multiple blood lipids with a combination of a fibrate and a statin. The study enrolled 10,251 adults beginning in 2001.

The Framingham Heart Study (FHS) is dedicated to identifying common factors or characteristics that contribute to cardiovascular disease (CVD). In 1948, an original cohort of 5,209 men and women between 30 and 62 years old were recruited from Framingham, MA. An Offspring Cohort began in 1971, an Omni Cohort in 1994, a Third Generation Cohort in 2002, a New Offspring Spouse Cohort in 2004 and a Second...

The Nurses' Health Studies (NHS) are long-running, questionnaire-based studies on women's health. The study was started in 1976 and expanded in 1989 and includes data from 238,000 female, nurse-participants. The study focuses on cancer, cardiovascular disease and risk factors for chronic health issues in women. The dataset includes both survey data and biospecimens.

An NHLBI-funded observational study of risk factors for cardiovascular disease in adults 65 years or older. Starting in 1989, and continuing through 1999, participants underwent annual extensive clinical examinations. Measurements included traditional risk factors such as blood pressure and lipids as well as measures of subclinical disease, including echocardiography of the heart, carotid ultrasound,...

The Jackson Heart Study (JHS) is a population-based longitudinal study based in Jackson, Mississippi that investigates cardiovascular disease among African Americans, including congenital heart disease, strokes, and high blood pressure. The primary objective is to investigate cardiovascular disease in African Americans in order to better address health disparities. The JHS is a community-based observational...